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Abstract Aim and Background: Studying the role of background causes and biomarkers on early onset cardiovascular diseases&#039; incidence as one important issue is need for prevention of these diseases. The purpose of this study was to identify the role of background factors and biomarkers for early onset cardiovascular diseases&#039; incidence. Methods and Materials: In a descriptive study with cross-sectional design, 154 outpatients with cardiovascular diseases who attended to Tehran Heart Center and 181 healthy persons among who associated with these patients were select by convenience sampling during November 2012 to March 2013. Data were collect by semi-structured interview and demographic-disease characteristics questionnaire, then analyzed by Chi-square, Independent t test and Logistic Regression with predictive analyses software (PASW). Findings: Low family income (OR=8.325; P<0.001), higher sedentary behaviors (OR=9.671; P<0.001), loss of regular exercise (OR=5.609; P<0.002), cigarette smoking (OR=3.320; P<0.009), high triglyceride level (OR=5.125; P<0.001), high blood&nbsp; pressure (OR=6.183; P <0.004), (kg/m2>25 th ) Body Mass Index (OR=7.133; P<0.005), (&ge; 200 mg/dL) higher total cholesterol (OR=6.108; P<0.001), (&le; 35 mg/dL) decreased HDL cholesterol (OR=5.589; P<0.002) and (&ge;130 mg/dL) increased LDL cholesterol (OR=5/094; P<0.005) significantly predicted early onset cardiovascular diseases&#039; incidence (P<0.05). Conclusions: Family income level, sedentary behaviors and loss of regular exercise, cigarette smoking and biomarkers are important in early onset cardiovascular diseases&#039; incidence. Therefore, it is matter to intervention in these causes for prevention of early onset cardiovascular diseases&#039; incidence.

Keywords: Background Factors, Biomarkers, Cardiovascular Diseases

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