Aim and Background: Recent studies on depression disorders have shown constraints and deficiencies in self-compassion of these patients. Therefore, in this study, we identify the weaknesses of previous studies with the aim of providing an analytical pattern of pathology of depression focusing on self-compassion for depressed Iranian patients.

Methods and Materials: The present paper is based on the meta-analysis of previous works and papers. Accordingly, by analyzing the previous studies related to the disorders from databases such as Science Direct and Civilica, we extracted the most important indicators related to self-compassion for depressed patients out of 12 articles.

Findings: After qualitative and quantitative evaluation of Iranian and foreign studies, final synthesis was ultimately done on the 12 articles. The synthesis of articles related to the effect of self-compassion on depression and its intermediary factors showed that depression is closely related to emotions and that is of great importance in most of the studies conducted in this area.

Conclusions: It is possible to prevent and treat depression through self-compassion by pathology in three critical areas of emotion, including emotion regulation, emotional security and expressing emotion.