Ahmadi A, Banaei Borojeni J, Keshavarz S, Eftekhari E. The Effect of Eight Weeks of Combined Exercises on Plasma Kynurenine Levels and Body Composition of Type 2 Diabetic Men. RBS 2024; 22 (3) :406-422
URL:
http://rbs.mui.ac.ir/article-1-1743-en.html
1- Sport Medicine Research Center, Najafabad Branch, Islamic Azad University, Najafabad.Iran
2- Sport Medicine Research Center, Najafabad Branch, Islamic Azad University, Najafabad, Iran , jamshid.banaii@gmail.com
3- Sport Medicine Research Center, Najafabad Branch, Islamic Azad University, Najafabad, Iran
Abstract: (728 Views)
Aim and Background: Diabetes is one of the non-communicable diseases that cause many effects on the body. Today, the chosen lifestyle and daily behaviors of the individual, especially sports activities, are used a lot to reduce the complications caused by it. The purpose of this study was to evaluate the effect of eight weeks of combined exercises on the plasma levels of kynurenine and body composition of type 2 diabetic men.
Methods and Materials: In this research, subjects included 24 men with type 2 diabetes with an age range of 60.29 ± 4.00 (years), weight 87.37 ± 6.83 (kg), height 57.57 ± 0.11. 1 (m), body mass index (kg/m2) 36.12 ± 9.09, fat mass (percent) 28.77 ± 1.94, muscle mass (kg) 26.82 ± 1.66, average blood sugar Three months (A1C) 7.74 ± 0.41, fasting blood sugar (mg/dL) 163.79 ± 2.14, medical history (years) 3.92 ± 0.50, voluntarily They were selected and randomly divided into two groups, the experimental group (12 people) and the control group (12 people). The experimental group for eight weeks, three sessions of 60 to 80 minutes each week, combined exercises including resistance exercises (four exercises for the upper and lower muscles with an intensity of 60 to 70%, one maximum repetition) and aerobics (with an intensity of 60% of the maximum oxygen consumption for 15 minutes) and the control group had no training during this period. In order to measure research variables, blood sampling was done 48 hours before the start of the first training session and also 48 hours after the last training session while all subjects were fasting. ELISA method was used to measure kynurenine plasma levels. To analyze the data, the statistical test of correlated t-test, independent t-test and Shapiro-Wilk test was used to normalize the data at a significance level of 0.05, with SPSS version 22 software.
Findings: The results of the present study showed that eight weeks of combined exercises reduced the plasma levels of kynurenine. In addition, combined training led to a decrease in fat mass and body mass index and an increase in fat-free mass.
Conclusions: Based on the results of this research, it is suggested to use combined exercises to reduce the plasma levels of kynurenine and improve the body composition of type 2 diabetic men.
Type of Study:
Research |
Subject:
Special Received: 2024/04/26 | Accepted: 2024/10/1 | Published: 2024/10/1