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Aim and Background: Schizophrenia, as one of the major psychiatric disorders, usually results in decreased quality of life and level of functioning. This study aimed to follow-up the course, severity, and quality of life in patients with schizophrenia. Methods and Materials: This study was 6 months follow-up on 20 patients with schizophrenia who were admitted to Noor Hospital, Isfahan, Iran. Each patient was evaluated on admission day, discharge, three and six months after discharge. The severity of symptoms and life quality were measured by Positive and Negative Symptoms Scale and quality of life questionnaire. Findings: Mean scores of severity on the admission day was significantly more than discharge and three and six months after discharge (P = 0.001). There was no significant difference between discharge and three and six months after discharge regarding severity of symptoms. Mean scores of quality of life were significantly greater at the time of discharge than three and six months after that (P = 0.03). There were no significant differences observed between discharge time and six month after it, and also between the third and sixth months after discharge. Conclusions: It can be acknowledged that hospitalization of patients can be effective in decreasing the symptom severity and increasing quality of life.

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Aim and Background: The present study aimed to investigate the symptom severity and quality of life in patients suffering from bipolar disorder. Methods and Materials: This longitudinal and prospective study was done on 20 patients with bipolar type I disorder who were hospitalized in Noor Hospital of Isfahan, Iran. Patients were evaluated before hospitalization, at the time of discharge, 3 and 6 months after discharge. Patient’s mood symptoms severity and quality of life were evaluated by Young Mania Rating Scale (YMRS) and World Health Organization’s Quality of Life Questionnaire. Findings: Repeated measure analysis of variance showed that the mean of mood symptoms severity at the time of hospitalization was significantly higher than its mean at the time of discharge, as well as 3 and 6 months after it. However, there was no significant difference between the scores of quality of life at discharge, and 3 and 6 months after discharge. Conclusions: It can be acknowledged that patient’s hospitalization was effective in decreasing the symptom severity and increasing quality of life at the time of discharge and it remained the same through the next stages.