Abstract Aim and Background: This study aims to predict self-care behavior based on the characteristics of Hardiness , hope and dysfunctional attitudes in patients with type 2 diabetes. Methods and Materials: Study design was a descriptive correlation method. The target population was all patients with diabetes type 2 who referred to Isfahan Endocrine and Metabolism Centers. The sample consisted of 120 patients. The multi-stage cluster sampling was used for the sample selection . The instrument employed in this research was Self – care Scale, hardiness Questinnaire, Hope Scale and Dysfunctional Attitudes Scale . The Pearson correlation and multiple regression analysis with stepwise method were used to analyze the data. Findings: Analysis of the data showed that the only interaction between hope and dysfunctional attitudes have been able to predict self-care (r=0.191,p<0.05). But separately there is no relationship between hardiness , hope, dysfunctional attitudes and self-care. Conclusions: Interaction of dysfunctional attitudes and hope are able to predict self-care behavior. Therefore, the program which modify dysfunctional attitude and enhance Life Expectancy seems to increase self-care behavior.
