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Aim and Background: Reducing sex hormones in men with various physical and psychological problems, including depression, decreased physical activity, impairment in memory, and executive functions.The purpose of this study was to compare mental health between andropause and normal men in order to identify the psychological aspects of andropause . Methods and Materials: The present study was a causal-comparative study and 150 men were selected as the research sample from the male employees of Tehran Medical University who aged 45-65 years. After filling Androgen Deficiency of Aging Men (ADAM) questionnaire and General Health Questionnaire (GHQ), participants divided into two groups; normal and andropause clinical diagnosis. Who received androgen-deficiency syndrome by the questionnaire referred to the lab in order to biochemical diagnosis of andropause. Findings: There were significant differences between this three groups in terms of physical symptoms, social function, anxiety and depression, and those who received a laboratory diagnosis of andropause reported more depression and anxiety . Conclusions: According to the result, who received andropause laboratory diagnosis had severe depression and anxiety that indicates the necessity of using psychotherapy along with hormonal and other therapies for andropause .

Keywords: Aging, Andropause, Men, Mental health.

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