Aim and Background: Diabetes mellitus is one of the most common chronic diseases and is one of the biggest health problems in all countries. The most important strategy for controlling chronic patients is self-care behaviors. The purpose of this study was to compare the effect of Interactive Diabetes Management Training (IDMT) and Stress Inoculation Training (SIT) on self-care in type II diabetic patients.

Methods and Materials: This was a semi-experimental research and the population of this study included 2450 diabetic patients in Isfahan's Um Al-Benin Clinic, 39 of whom were selected through a convenient sampling method and randomly assigned to two groups of control and one control group. Groups Summary of Diabetes Self-Care Activities (SDSCA) for diabetic patients completed before and after education. Experimental group one, (SIT), and two groups of (IDMT) training received a weekly and group-based 90-minute training session. But the control group did not receive these training. The research findings were analyzed using Multivariate Analysis of Covariance (MANCOVA) and SPSS-19 software.

Findings: IDMT and SIT were effective in diabetic patient’s self-care and both training increased self-care for participants. But there was no significant difference between the two methods of intervention (p ≤.319).

Conclusions: SIT and IDMT can be used as an effective interventional method for increasing self-care in diabetic patients.