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Aim and Background: Schizophrenia, as one of the major psychiatric disorders, usually results in decreased quality of life and level of functioning. This study aimed to follow-up the course, severity, and quality of life in patients with schizophrenia. Methods and Materials: This study was 6 months follow-up on 20 patients with schizophrenia who were admitted to Noor Hospital, Isfahan, Iran. Each patient was evaluated on admission day, discharge, three and six months after discharge. The severity of symptoms and life quality were measured by Positive and Negative Symptoms Scale and quality of life questionnaire. Findings: Mean scores of severity on the admission day was significantly more than discharge and three and six months after discharge (P = 0.001). There was no significant difference between discharge and three and six months after discharge regarding severity of symptoms. Mean scores of quality of life were significantly greater at the time of discharge than three and six months after that (P = 0.03). There were no significant differences observed between discharge time and six month after it, and also between the third and sixth months after discharge. Conclusions: It can be acknowledged that hospitalization of patients can be effective in decreasing the symptom severity and increasing quality of life.

Keywords: Follow-up, Course, Schizophrenia, Severity, Quality of life

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