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Background& Aim: Substance abuse is associated with high prevalence of psychiatric disorders including mood disorders (especially depression), personality disorders and psychosis. The purpose of this study was to investigate the effect of methadone and its result on substance induced depression-symptoms among IV drug abusers of Kashan prison in 1384. Method & Materials: This is a semi-experimental study. A two part questionnaire including demographic data and Beck Depression Inventory (BDI) were administered to participants by the prison clinical psychologist. After insuring privacy, performing the questionnaire, and interviewing with each participant done by three psychologists, oral methadone was prescribed to non-excluded participants. After three months of taking methadone, they were re-evaluated by BDI and re- interviewed by psychologists for making diagnoses based on DSM-IV. Data were analyzed by paired T-test.   Findings: Based on clinical interview, from the 35 participants, 26(74.2%) were diagnosed as having Major Depressive Disorder , 2 of whom were excluded from the study and referred for further follow up because of suicidal thinking .The rest 9 participants (25.7%) were not depressed. After the intervention, of all 24, 19 ones(79.16%) showed relative improvement and 5(20.83%) remained unchanged. A significant reduction was found in the mean BDI score after the intervention(p Conclusion: This study showed that methadone can reduce depression severity in IV drug abusers.

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Aim and Background: Negative and positive emotional states, temptation, and anxiety are among the most important risk factors for addiction. This research aimed to study the effect of dialectical behavior therapy (DBT)-based emotional management training on anxiety and temptation in patients with drug abuse. Methods and Materials: This was an experimental research with pretest/posttest method and control group. To select the sample, the available sampling method was used. Among patients with substance abuse in addiction treatment centers in Ahwaz City, Iran, based on clinical interviews, 28 were selected. They were randomly divided into two equal groups of experimental and control. Both groups passed the leaving and detoxification steps. The experimental group received 10 sessions of dialectical behavior therapy-based emotional management training, but the control group did not receive any intervention. The research tools were demographic questionnaire, Craving Believes Questionnaire (CBQ), and Beck Anxiety Inventory (BAI). Findings: After the intervention, there were significant differences between experimental and control groups regarding anxiety and temptation (P < 0.001 for both). In other words, the rate of anxiety and temptation in experimental group significantly decreased in comparison with pretest and control group. Conclusions: The current study indicated that dialectical behavior therapy-based emotional management training would be an appropriate treatment for university students in order to decrease the symptoms of anxiety and temptation in those with drug abuse.