Mostaghni isfahani F, Taghian F, Jalali dehkordi K, Mousavi M S. The Effect of Aerobic Exercise and Aphrodite Supplementation on the Levels of Some Antioxidant Factors in Postmenopausal Women with Depression. RBS 2025; 23 (2) :313-321
URL:
http://rbs.mui.ac.ir/article-1-1947-en.html
1- PhD Student, Department of Sports Physiology, Isf.C., Islamic Azad University, Isfahan, Iran.
2- Professor, Department of Sports Physiology, Isf.C., Islamic Azad University, Isfahan, Iran. , f.taghian@iau.ac.ir
3- Associate Professor, Department of Sports Physiology, Isf.C., Islamic Azad University, Isfahan, Iran.
4- Associate Professor, Department of Midwifery, Community Health Research Center, Isf.C., Islamic Azad University, Isfahan, Iran.
Abstract: (1056 Views)
Aim and Background: The life of menopausal women is the result of a series of psychological changes that occur due to the decrease in sex hormones and alterations in neurohormones that determine etiopathogenetics. Changes in the neuroendocrine and neurotransmitter systems associated with estrogen reduction negatively affect women's psychophysical health. They can explain, at least in part, the increased incidence of mental and neurological disorders in the postmenopausal period. The present study aimed to investigate the effect of twelve weeks of moderate-intensity aerobic exercise and Aphrodite supplementation on the levels of some neuronal factors and neurotransmitters related to mental disorders and menopausal women.
Methods and Materials: 102 postmenopausal women living in Isfahan city who had mild depression according to the Hamilton questionnaire were divided into four groups according to the inclusion criteria, including a control group, aerobic exercise group, Aphrodite supplement, and aerobic exercise + Aphrodite supplement. The aerobic exercise program of walking and light running with moderate intensity of 65 to 70% of the heart rate was performed on a treadmill, and the dose of Aphrodite supplement was two doses per day.
Findings: The results showed a significant increase in plasma levels of superoxide dismutase (SOD) and glutathione (GSH) (P<0.05). These antioxidants can either prevent the production of oxidative species or reduce the oxidative effects of reactive oxygen species (ROS). This increase was significantly greater in the aerobic exercise group combined with Aphrodit upplement compared to the other groups (P<0.05). Additionally, the level of malondialdehyde (MDA) significantly decreased (P<0.05)
Conclusions: According to the results, it seems that taking the Aphrodite supplement along with aerobic exercise has a synergistic effect on improving physical and psychological symptoms in menopausal women.
Type of Study:
Research |
Subject:
Special Received: 2025/05/14 | Accepted: 2025/08/13 | Published: 2025/09/1